Isotonicity Calculations Quiz
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Question 1 of 10
1. Question
How many grams of sodium chloride are needed for the following prescription?
Tobramycin 0.8 g (E value: 0.07)
Sodium chloride qs
Purified water ad 15 ml
Make isotonic solution
Place one drop in each eye BID x7 daysRound answer to the nearest thousandth. Do not include units.
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Question 2 of 10
2. Question
What is the E value (NaCl equivalent) of urea with an i value of 2.6? Round answer to the nearest tenth. Do not include units.
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Question 3 of 10
3. Question
A pharmacy has to compound 30 ml of a 1% solution of atropine sulfate. How many grams of sodium chloride are needed? (Freezing point depression of Atropine sulfate 0.07, sodium chloride 0.58). Round answer to the nearest thousandth. DO not include units.
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Question 4 of 10
4. Question
Ephedrine HCl 2g E = 0.3
Chlorobutol 0.5g E = 0.24
KCl Qs E = 0.4
Distilled Water 200 mL
Determine the amount of KCl in grams needed to make the solution isotonic? Round answer to the nearest tenth. Do not include units.Correct
Incorrect

Question 5 of 10
5. Question
What volume of purified water in milliliters is needed to make an isotonic solution of 125 ml of 15% phenobarbital sodium (E value of 0.24)? Round to the nearest whole number. Do not include units.
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Question 6 of 10
6. Question
Ephedrine Sulfate 1% E = 0.23
Dextrose Qs E = 0.16
Isotonic solution 50 mL
How many milligrams of dextrose would need to be added to make the solution isotonic with blood? Round answer to the nearest whole number. Do not include units.Correct
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Question 7 of 10
7. Question
How many grams of Urea are needed for the following prescription?
Zinc chloride 0.7 g (E value: 0.62)
Tropicamide 1 % (E value: 0.59)
Urea qs (E= 0.52)
Purified Water 250 ml
Make isotonic solutionRound answer to the nearest thousandth. Do not include units.
Correct
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Question 8 of 10
8. Question
Tobramycin 0.8% E = 0.07
Vancomycin 25mg/mL E = 0.05
Boric Acid qs E = 0.52
Sterile water for injection qs 50 mL
Make isotonic solution
Determine the amount of boric acid in grams that should be used in compounding this formulation.Correct
Incorrect

Question 9 of 10
9. Question
Pilocarpine nitrate 0.5% E = 0.23
Boric Acid 5mg/mL E = 0.52
Sterile water for injection qs 30 mL
Make isotonic solution
Calculate the volume of 0.9% sodium chloride in milliliters required to dispense the above formulation.Correct
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Question 10 of 10
10. Question
Atropine Sulfate (fz pt = 0.07 °C) 1%
Boric Acid qs
Water for injection 60 mL
Make isoton. Sol.
Calculate the amount of boric acid (E=0.52) in milligrams required to make the following solution isotonic with tears. Round answer to the nearest whole number. Do not include units.Correct
Incorrect