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Welcome to the NAPLEX Calculations Practice Quiz. There are 30 NAPLEX type calculations questions in this quiz. Questions cover pertinent calculations topics described in the NAPLEX blueprint. All the best!
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Question 1 of 30
1. Question
A prescription reads “Diphenhydramine 50 mg p.o. h.s. x 30 days”. Calculate the dispensed quantity of drug in milliliters for a 20day supply if the concentration is (12.5 mg/5 cc).
Correct
Incorrect
The correct answer is 400

Question 2 of 30
2. Question
What is the day supply of a 5mL bottle of timolol if a patient is placed on 2 gtt OU BID assuming 15 drops per mL?
Correct
Incorrect
The correct answer is 9

Question 3 of 30
3. Question
The specific gravity of alcohol is 0.815. What is the specific volume? Round to the nearest hundredth.
Correct
Incorrect
The correct answer is 1.23

Question 4 of 30
4. Question
What is the volume, in milliliters, of 2 lb of benzyl benzoate having a specific gravity of 1.120? Round to the nearest hundredth. Do not include units.
Correct
Incorrect
The correct answer is 810.71

Question 5 of 30
5. Question
What is the amount of protein in grams needed by a 57 y/o female who weighs 124 lbs and has a protein requirement of 1 g/kg? Round to the nearest tenth. Do not include units.
Correct
Incorrect
The correct answer is 56.4

Question 6 of 30
6. Question
JM is a patient in the ICU (6’1” and 256 pounds). He is currently receiving a 3in1 PN at 125 mL/h. The PN is 12.1% w/v dextrose and 4.7% w/v protein. The prescriber wants the patient’s protein intake from the PN to be 1.4 g/kg IBW per day. By how many grams will the current protein content need to be reduced to achieve this? Round to the nearest hundredth. Do not include units.
Correct
Incorrect
The correct answer is 29.14

Question 7 of 30
7. Question
How many milliliters of hydrocortisone liquid (25 mg/mL) will be needed to prepare 28000 mg of a 0.35% (w/w) cream? Round to the nearest hundredth. Do not include units.
Correct
Incorrect
The correct answer is 3.92

Question 8 of 30
8. Question
What is the percentage strength (v/v) of a solution of 650 g of a liquid with a specific gravity of 0.6 in enough water to make 6000 mL? Round to the nearest tenth. Do not include percent sign.
Correct
Incorrect
The correct answer is 18.1

Question 9 of 30
9. Question
If 750 mL of a 28% (v/v) solution of methyl salicylate is diluted to a 2liter solution, what will be the percentage strength (v/v)? Round to the nearest tenth. Do not include percent sign.
Correct
Incorrect
The correct answer is 10.5

Question 10 of 30
10. Question
What proportion of 20% zinc oxide and 75% zinc oxide do you need to make 50% zinc oxide?
Correct
Incorrect

Question 11 of 30
11. Question
What is the pH of a solution if the hydroxide ion concentration is 4.2 x 10^{5} M? Round to the nearest hundredth. Do not include units.
Correct
Incorrect
The correct answer is 9.62

Question 12 of 30
12. Question
What would the pK_{b} value be of a solution that has a pK_{a} value of 4.2 and a 5:4 molar ratio concentration of base to salt? Round to the nearest tenth. Do not include units.
Correct
Incorrect
The correct answer is 9.8

Question 13 of 30
13. Question
A liquid suspension contains 0.75% w/v of the active drug. If one drop is 0.05 mL, how many µg of drug is contained in each drop? Round to the nearest whole number. Do not include units.
Correct
Incorrect
The correct answer is 375

Question 14 of 30
14. Question
How many milliliters of U500 needs to be added to a 500 mL bag of D_{5}W to create a concentration of 0.1 units/mL? Round to the nearest tenth. Do not include units.
Correct
Incorrect
The correct answer is 0.1

Question 15 of 30
15. Question
How many grams of potassium chloride should be used to prepare 200 mL of a potassium chloride solution containing 2.5 mEq of K^{+} per mL? Round to the nearest hundredth. Do not include units.
Correct
Incorrect
The correct answer is 37.28

Question 16 of 30
16. Question
A potassium phosphate injection contains 150 mg of monobasic potassium phosphate (KH_{2}PO_{4}) and 300 mg of dibasic potassium phosphate (K_{2}HPO_{4}) per millimeter. If 10 mL of the injection is added to a 250 mL D_{5}W bag, calculate the milliequivalent of K^{+} in the solution? (MW of KH_{2}PO_{4} = 136, MW of K_{2}HPO_{4} = 174). Round to the nearest whole number. Do not include units.
Correct
Incorrect
The correct answer is 46

Question 17 of 30
17. Question
What is the osmolarity of an 8.4% w/v solution of sodium bicarbonate (NaHCO_{3}:MW= 84)? Round to the nearest whole number. Do not include units.
Correct
Incorrect
The correct answer is 2000

Question 18 of 30
18. Question
A patient experiencing preterm labor is to be given magnesium sulfate at a rate of 3 g/h. The pharmacy provides 500 mL of a 4% solution. Calculate the osmolarity of the solution. Round to the nearest whole number. Do not include units.
Correct
Incorrect
The correct answer is 667

Question 19 of 30
19. Question
A pharmacy has to compound 150 mL of a 1% solution of ephedrine sulfate. How many grams of sodium chloride should be used to make it isotonic? The sodium chloride equivalent of ephedrine sulfate is 0.23. Round to the nearest whole number. Do not include units.
Correct
Incorrect
The correct answer is 1

Question 20 of 30
20. Question
Ingredient D (E=0.18) 3%
Ingredient G (E= 0.15) 0.2%
Boric Acid qs
Purified Water ad 60 mL
Sig. For the eye
How many milliliters of purified water should be used in compounding the prescription? Round to the nearest tenth. Do not include units.
Correct
Incorrect
The correct answer is 5.6

Question 21 of 30
21. Question
A patient brings in a prescription to the pharmacy for amoxicillin 250 mg BID x 10 days. You dispensed 4 ounces of amoxicillin 125 mg/5 mL. How many days short was the filled prescription? Round to the nearest whole number. Do not include units.
Correct
Incorrect
The correct answer is 4

Question 22 of 30
22. Question
A bottle of amoxicillin contains 100 mg/5 mL (94 mL of water added for a 100 mL bottle) the doctor wants the patient to take 80 mg per teaspoon (for ease of dosing) BID x 5 days. How many milliliters of water needs to be added for a concentration of 80 mg per teaspoon? Round to the nearest whole number. Do not include units.
Correct
Incorrect
The correct answer is 119

Question 23 of 30
23. Question
The initial activity of a radiopharmaceutical is 50 mCi/mL. Calculate the amount that should be dispensed to provide a dose of 25 mCi if the activity at the time of administration is 5 mCi/mL. Round to the nearest whole number. Do not include units.
Correct
Incorrect
The correct answer is 5

Question 24 of 30
24. Question
Based on the formula below, how many grams of propylene glycol (specific gravity=1.04) is required to compound a 600 mL preparation.
Diltiazem HCl 4 g
Propylene Glycol 20 mL
Hyrdroxyethylcellulose 2 g
Sterile water for injection qs ad 200 mL
Round to the nearest tenth. Do not include units.
Correct
Incorrect
The correct answer is 62.4

Question 25 of 30
25. Question
The following prescription is for an eye ointment. How much of each ingredient will be needed to make 100 tubes?
Sulfacetamide sodium 6% w/w
Prednisolone Acetate 0.1% w/w
Phenylmercuric acetate 0.007% w/w
Mineral oil 0.75% w/w
Petroleum qs ad 4 g
Correct
Incorrect

Question 26 of 30
26. Question
What is the percent error if tasked with weighing 120 mg of atropine sulfate on a class A prescription balance with a sensitivity requirement of 6 mg? Round to the nearest whole number. Do not include percent sign.
Correct
Incorrect
The correct answer is 5

Question 27 of 30
27. Question
A prescription calls for 50 milligrams of chlorpheniramine maleate. Using a prescription balance with a sensitivity requirement of 6 milligrams, explain how you would obtain the required amount of chlorpheniramine maleate with an error not greater than 5%.
Correct
Incorrect

Question 28 of 30
28. Question
Drug X is to be administered to elderly patients at a maximum rate of 65 mg/min to avoid respiratory complications. What is the maximum infusion rate in mL/min for a solution containing 30 mg/mL of drug in 200 mL of normal saline? Round to the nearest hundredth. Do not include units.
Correct
Incorrect
The correct answer is 2.17

Question 29 of 30
29. Question
A drug is to be administered to pediatric patients at a maximum rate of 3 mg/min. What is the maximum rate in mL/min for a 150 mL D_{5}W solution with a drug concentration of 30 mg/mL? Round to the nearest tenth. Do not include units.
Correct
Incorrect
The correct answer is 0.1

Question 30 of 30
30. Question
A patient was administered 500 mL of D_{10}W at a rate of 40 mL/h. If the infusion begun at 5 A.M. at what time was it completed?
Correct
Incorrect